María Soraya Sáenz de Santamaría Antón (born 10 June 1971) is a Spanish People's Party politician who has served as Member of Parliament (MP) for Madrid since 2004. She previously served in the Rajoy Government as Deputy Prime Minister of Spain, Minister of the Presidency from December 2011 to June 2018 and Minister for Territorial Administrations from November 2016 to June 2018. She served in the Cabinet as interim Health Minister and interim Justice Minister in 2014 and as Spokesperson of the Government from 2011 to 2016.
She previously served as executive secretary of Territorial Policy of Partido Popular. In the 9th Legislature she was appointed by prime minister Mariano Rajoy as the Popular Party spokesperson in the Congress of Deputies, replacing Eduardo Zaplana.
After Mariano Rajoy dismissed President of the Generalitat of Catalonia Carles Puigdemont, Sáenz de Santamaría was given responsibility for overseeing the functions of the Generalitat of Catalonia.