Saundra Santiago (born April 13, 1957) is an American actress. She portrayed Det. Gina Calabrese on 1980s television series Miami Vice.
Santiago is the daughter of a Cuban father and a Puerto Rican mother. Raised in the South Bronx, New York City, where she attended Our Lady of Victory grammar school. When she was 13 years old her family moved to Homestead, Florida.
Santiago graduated from South Dade Senior High School and attended the University of Miami on a scholarship, majoring in psychology. As a University of Miami student, she became interested in acting. After graduation, she went on to post-graduate study in theater and arts at Southern Methodist University, eventually earning a master's degree. Santiago joined the company of regional summer stock theater, Timber Lake Playhouse, Mount Carroll, Illinois, performing many roles including Maria in West Side Story in the 1980 season.