Reginald Alfred Bush Jr. (born March 2, 1985) is a former American football running back. He played college football at USC, where he earned consensus All-American honors twice and won the Heisman Trophy as the most outstanding player in the nation. He was drafted by the New Orleans Saints second overall in the 2006 NFL Draft. While with the Saints, Bush was named an All-Pro in 2008 and won Super Bowl XLIV in 2010 over the Indianapolis Colts. He also played for the Buffalo Bills, Miami Dolphins, Detroit Lions, and San Francisco 49ers.
Bush also won the 2005 Doak Walker and Walter Camp awards. However, allegations that he received improper benefits were central to an NCAA investigation of the USC football program that led to severe NCAA sanctions against USC, including a two-year postseason ban and the vacating of wins from the 2004 championship season. As a result, Bush forfeited his Heisman Trophy.