Panagiotis Tachtsidis (Greek: Παναγιώτης Ταχτσίδης; born 15 February 1991) is a Greek professional footballer who plays as a midfielder for Lecce and the Greece national team.
Tachtsidis was scouted by Toni Savevski, the head of AEK Athens's youth academy at the time, and signed his first professional contract with AEK on 1 November 2007. Shortly after signing his first professional contract, Tachtsidis made his debut for AEK in the Greek Cup against Fostiras. On 27 January 2009, he became the youngest player to have ever played for AEK in the Greek League when he played against Thrasyvoulos, being 16 years and 348 days old; that record, however, has since been surpassed by Taxiarchis Fountas, also for AEK. Against Thrasyvoulos, Tachtsidis scored the winning goal in the 92nd minute to give his team the three points.
On 21 April 2010, Tachtsidis completed a move to Italian club Genoa that had already been previously agreed upon in January 2010.