Mohamed Safwat (Arabic: محمد صفوت; born 19 September 1990) is an Egyptian tennis player. Safwat has been a regular player on the Egypt Davis Cup team since 2009. He is currently the Egyptian No. 1, and the second-highest ranked Arab player behind Malek Jaziri.
In 2016, Safwat was the first Egyptian player since 1997 to reach the final of a Challenger tournament when he reached the final in Kenitra, before losing to Maximilian Marterer in straight sets. He also reached the semifinals at the Challenger tournament in Launceston in 2017, eventually losing to Mitchell Krueger.
In 2018, Safwat beat No. 3 seed and top 100 player Jordan Thompson en route to his second Challenger singles final in Anning, where he lost to Prajnesh Gunneswaran. Safwat qualified for his first Grand Slam at the 2018 French Open as a lucky loser, where he lost to Grigor Dimitrov in straight sets. He was the first man from Egypt to play in a Grand Slam tennis tournament's main singles draw in 22 years.