Matías Agustín Silvestre (born 25 September 1984) is an Argentine professional footballer who plays for Empoli as a centre-back.
Silvestre began his career with Argentine club Boca Juniors, where he would go on to make his league debut on 23 March 2003 in a 3–1 win over Lanús. Silvestre soon was inserted into the Boca Juniors starting line-up and between 2003 and 2007, he went on to make 63 league appearances, scoring six goals. He was used as both a central defender and a right full-back during his spell with the club. Following an impressive 2007 season of the club, Silvestre was transferred to Catania in the Serie A.
During the 2008 January transfer window, Silvestre transferred to Sicilian club Catania on loan. His first six months at Catania was not so great as he was not part of then-coach Silvio Baldini's starting team, making just 11 appearances, just five as a starter. However, his loan was nonetheless made permanent in the summer of 2008 for €2.043 million after Walter Zenga was appointed head coach, following the sacking of Baldini. He soon became an instrumental part of Catania's first team and was a major influence on their fairly successful 2008–09 season as the club avoided relegation for the third consecutive season.