Karine Vanasse (born 24 November 1983) is a French Canadian actress, who had roles in the films Polytechnique, Séraphin: Heart of Stone, Switch and Set Me Free (Emporte-moi). Internationally she is best known for her roles as Colette Valois in Pan Am and Margaux LeMarchal in Revenge, both U.S. television series.
Vanasse was born in Drummondville, Quebec, the daughter of Conrad Vanasse, a council worker, and Renée (née Gamache), who was her manager at the beginning of her career. At the age of nine, Vanasse expressed her desire to sing or to act and she fulfilled that wish when she appeared in the teen show Club des 100 watts after winning a "lip sync" competition. It was then, with the help of her mother, that Vanasse began to audition for, and take part in, TV commercials and to play minor and supporting roles in various French Canadian TV movies.
In 1998, the production company now known as Motion International asked Vanasse to co-host a Québec-based children's science show, Les Débrouillards. Producer Lorraine Richard and director Léa Pool spotted her there, and offered Vanasse her first big break in the role of Hanna in Set Me Free (Emporte-moi) (1999), a story of a teenager trying to find her identity in a tormented family environment. The film was presented at forty festivals, and shown in twenty countries. Her performance was highly acclaimed both nationally and internationally and earned her the 2000 Best Actress Jutra Award.