Jeison Fabián Murillo Cerón (born 27 May 1992) is a Colombian professional footballer who plays as a centre-back for Italian club Sampdoria, on loan from Valencia and the Colombia national team.
Born in Cali, Murillo signed with Udinese Calcio in Italy shortly after his 18th birthday, being immediately loaned to Granada CF as part of the partnership agreement between both clubs. He spent his first year in Spain with the reserves, in the regional leagues.
In early February 2012, Murillo was definitely bought by the Andalusians, but spent the following seasons on loan to clubs also in the country, Cádiz CF and UD Las Palmas. He scored four official goals in his first year as a professional, including a brace on 9 March 2013 in a 3–2 away win against UD Almería for the Segunda División championship; with both teams, he appeared in the promotion playoffs, where both teams were unsuccessful.