Fabio Pisacane (born 28 January 1986) is an Italian footballer who plays for Cagliari in Serie A as a defender.
Pisacane started his career at Genoa, where he was initially a member of the team's youth system. At the age of 14, however, he was diagnosed with Guillain-Barré syndrome, which seriously threatened his career, as it caused him to experience temporary paralysis in his limbs. After recovering, he was promoted to the reserve side, where he remained from 2003 to 2005. He made his professional debut during the 2005–06 season, while on loan with Ravenna. After several seasons in Serie C, he was signed by Chievo on a free transfer in 2008, but joined Lumezzane in a co-ownership deal, along with his Chievo teammates Tommaso Chiecchi and Amedeo Calliari. During the 2009–10 season, he left for Serie B side Ancona. During the 2010–11 season, he remained at Lumezzane along with Francesco Checcucci.