Caylee Marie Anthony (August 9, 2005 – 2008) was a two-year-old American girl who lived in Orlando, Florida (United States), with her mother, Casey Marie Anthony (born March 19, 1986), and her maternal grandparents, George and Cindy Anthony. On July 15, 2008, she was reported missing in a 9-1-1 call made by Cindy, who said she had not seen Caylee for 31 days and that Casey's car smelled like a dead body had been inside it. Cindy said Casey had given varied explanations as to Caylee's whereabouts before finally telling her that she had not seen Caylee for weeks. Casey lied to detectives, telling them Caylee had been kidnapped by a nanny on June 9, and that she had been trying to find her, too frightened to alert the authorities. She was charged with first-degree murder in October 2008 and pleaded not guilty.
On December 11, 2008, Caylee's skeletal remains were found with a blanket inside a trash bag in a wooded area near the family home. Investigative reports and trial testimony alternated between duct tape being found near the front of the skull and on the mouth of the skull. The medical examiner mentioned duct tape as one reason she ruled the death a homicide, but officially listed it as "death by undetermined means".